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RU administration before ovulation prolongs the proliferative phase. Treatment during the proliferative phase suppresses follicular development and postpones the estrogen and luteinizing hormone surge, but does not alter endometrial morphology. RU administration during the mid- and late-luteal phase brings on bleeding despite normal progesterone levels, sometimes followed by another episode of bleeding at the usual time of menstruation. It does not affect the menstrual cycle if administered after ovulation, but considerably slows down endometrial development and changes the level of estrogen and progesterone receptor concentration, enzyme activity, and production of likely to be progesterone-dependent substances.

The effect on endometrial development of postovulation RU administration impedes implantation. In addition, postovulation treatment with RU significantly increases uterine contractility. RU administration during early pregnancy influences uterine contractility and greatly increases the myometrium's sensitivity to prostaglandins.

RU's effect on myometrial sensitivity to prostaglandins may persist even during the 2nd trimester of pregnancy. These effects support the combined treatment of RU and a prostaglandin to terminate an early pregnancy. Electrocatalytic water splitting plays a vital role in the hydrogen fuel industry, but suffers from the lack of efficient non-platinum Pt hydrogen evolution reaction HER catalysts.

Metallic Ru has proven to be one of the promising candidates for the HER. However, the syntheses of Ru nanoparticles in previous reports require harsh reaction conditions such as high temperature or very strong external reductants. The present work provides a facile and green strategy to prepare non-Pt HER electrocatalysts and it can be applied to the development of new photo-and electrocatalysts.

Chen, X. Yang, C. Hou, K. Li and Y. Chen, J. A , , 7 , DOI: To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page. If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given. If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given.

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